Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.47 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971604 | 0.98 | ESR1 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL27655928 | 0.98 | ESR1 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25299360 | 0.98 | ESR1 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL27874664 | 0.98 | ESR1 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| Water SCHEMBL27360793 | 0.97 | ESR1 (0.54) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL9525088 | 0.86 | SLC6A4 (0.56) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL237613 | 0.83 | PTGS2 (0.56) | ESR1PTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL10442969 | 0.83 | PTGS2 (0.50) | ESR1PTGS2PTGS1LMNACYP2C9 | |
| SCHEMBL312147 | 0.82 | KMT2A (0.76) | ESR1HIF1AKMT2ARECQLSMN1; SMN2 | |
| SCHEMBL11201814 | 0.82 | ALOX15 (0.58) | KMT2ASMN1; SMN2ALOX15PTGS2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 277 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4222139-A1 | TOPICAL ADMINISTRATION OF 2- (DIETHYLAMINO) ETHYL 2- (4-ISOBUTYLPHENYL) PROPIONATE FOR TREATMENT OF DISEASES | TECHFIELDS INC. (US) | 2023-08-09 | — | — | EP | claimed |
| WO-2023134733-A1 | TREATMENT OF SIGNS, SYMPTOMS AND/OR COMPLICATIONS OF VIRAL, BACTERIAL, PROTOZOAL, AND/OR FUNGAL INFECTIONS BY HIGH PENETRATION PRODRUGS | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-07-20 | — | — | WO | claimed |
| CN-115974936-A | Preparation method and application of high-valence nickel catalyst for acetylene hydrochlorination | 绍兴七轩新材料科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-20180311186-A1 | PHARMACEUTICAL FORMULATION FOR BEDWETTING AND METHOD OF USE THEREOF | WELLESLEY PHARMACEUTICALS, LLC | 2018-11-01 | — | — | US | claimed |
| US-20180296676-A1 | PHARMACEUTICAL FORMULATION FOR REDUCING BLADDER SPASMS AND METHOD OF USE THEREOF | WELLESLEY PHARMACEUTICALS, LLC | 2018-10-18 | — | — | US | claimed |
| CN-107793307-A | The derivative of tetrahydro-iso-humulone, method of manufacture and use thereof | 金戴克斯医药有限责任公司 | 2018-03-13 | — | — | CN | claimed |
| CN-106619676-A | Painkiller for relieving toothache | 郑州郑先医药科技有限公司 | 2017-05-10 | — | — | CN | claimed |
| CN-103003228-B | Compounds based on ibuprofen, preparation methods, uses and pharmaceutical preparation thereof | HOU WENGE | 2015-03-25 | — | — | CN | claimed |
| CN-103254070-B | Method for preparing 2-(4-isobutylphenyl)propionate from 1-(4-isobutylphenyl)ethanol | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2014-11-05 | — | — | CN | claimed |
| CN-103254070-A | Method for preparing 2-(4-isobutylphenyl)propionate from 1-(4-isobutylphenyl)ethanol | UNIV QINGDAO SCIENCE & TECHNOLOGY | 2013-08-21 | — | — | CN | claimed |
| CN-103003228-A | Compounds based on ibuprofen, preparation methods, uses and pharmaceutical preparation thereof | HEILONGJIANG BAOQINGLONG BIOTECHNOLOGY CO LTD | 2013-03-27 | — | — | CN | claimed |
| CN-102388014-A | Synthesis method of chiral alpha-aryl propionic acid derivative | DSM IP ASSETS BV | 2012-03-21 | — | — | CN | claimed |
| EP-2418200-A1 | PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF- MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES | EMS S. A. (BR) | 2012-02-15 | — | — | EP | claimed |
| US-20070066571-A1 | Novel bisphosphonates having anti-inflammatory and/or pain-killing properties | STOCKEL RICHARD F | 2007-03-22 | — | — | US | claimed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| WO-2002072037-A1 | TOPICAL DERMAL ANAESTHETIC | VAN ENGELEN H WAYNE (US) | 2002-09-19 | — | — | WO | claimed |
| US-20020094343-A1 | TOPICAL DERMAL ANAESTHETIC | PATTERSON, RICHARD | 2002-07-18 | — | — | US | claimed |
| US-6416772-B1 | Topical dermal anaesthetic | PATTERSON, RICHARD | 2002-07-09 | — | — | US | claimed |
| CN-115959993-B | Synthesis method of 2-aryl propionic acid compound | 山东中医药大学 | 2025-01-07 | — | — | CN | disclosed |
| US-3988333-A | Tri-substituted aluminum salts or di-substituted aluminum salts of carboxyl group-containing, pharmaceutically effective compounds | TEIKOKU HORMONE MFG. CO., LTD. (JA) | 1976-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066571-A1 | Novel bisphosphonates having anti-inflammatory and/or pain-killing properties | ENPP2, CD47, SOST | ESR1 1284/4885HIF1A 1691/4885KMT2A 4761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.