SCHEMBL237613

SCHEMBL237613

CC(C)Cc1ccc(OC(=O)Oc2ccc(CC(C)C)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.56
PTGS1 P23219 3/20 0.52
CXCR1 P25024 3/20 0.52
CXCR2 P25025 3/20 0.52
LMNA P02545 2/20 0.52
CYP2C9 P11712 2/20 0.52
AKR1C3 P42330 2/20 0.52
ALB P02768 1/20 0.52
ESR1 P03372 1/20 0.52
ALOX5 P09917 1/20 0.52
RARB P10826 1/20 0.52
ADRB3 P13945 1/20 0.52
NFKB1 P19838 1/20 0.52
HTR2A P28223 1/20 0.52
NR1I3 Q14994 1/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
CXCL8 P10145 1/20 0.52
TSHR P16473 1/20 0.52
AKR1C2 P52895 1/20 0.52
BLM P54132 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237802 0.94 PTGS2 (0.52) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL248142 0.93 PTGS2 (0.51) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL21517639 0.86 PTGS2 (0.55) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL159833 0.86 PTGS2 (0.55) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL6273093 0.86 ELANE (0.58) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL20040901 0.85 PTGS2 (0.54) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL15899564 0.83 LDHA (0.51) PTGS2PTGS1LMNACYP2C9AKR1C3
SCHEMBL577068 0.83 ESR1 (0.57) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL9577301 0.83 PTGS2 (0.52) PTGS2PTGS1CXCR1CXCR2LMNA
SCHEMBL15899295 0.83 ACACB (0.44) PTGS2PTGS1CXCR1CXCR2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 285 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures COVESTRO DEUTSCHLAND AG (DE) 2026-04-14 US disclosed
EP-3055342-B1 PROCESS FOR PREPARING POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES USING A SALT OF A WEAK ACID COVESTRO DEUTSCHLAND AG (DE) 2026-03-04 EP disclosed
WO-2025228904-A1 LAYER STRUCTURE WITH AT LEAST TWO LAYERS HAVING DIFFERENT ENGRAVINGS COVESTRO DEUTSCHLAND AG (DE) 2025-11-06 WO disclosed
EP-4644131-A1 LAYER STRUCTURE COMPRISING AT LEAST TWO LAYERS HAVING DIFFERENT ENGRAVINGS Covestro Deutschland AG (DE) 2025-11-05 EP disclosed
US-12365775-B2 Process for partial colouring of plastic parts using solid colourants in colour- carrier layers COVESTRO DEUTSCHLAND AG (DE) 2025-07-22 US disclosed
US-20250205963-A1 METHOD FOR PRODUCING A PLASTIC MOLDING tooz technologies GmbH (DE) 2025-06-26 US disclosed
EP-4549163-A2 IMPROVED METHOD FOR PARTIAL COLOURING OF PLASTIC PARTS Covestro Deutschland AG (DE) 2025-05-07 EP disclosed
EP-2593288-B2 APPARATUS AND PROCESS FOR PRODUCING PRODUCTS FROM PIGMENT-CONTAINING POLYMER MIXTURES COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2025-04-16 EP disclosed
US-20250091332-A1 FILM STRUCTURE SUITABLE FOR RAPID LAMINATION COVESTRO DEUTSCHLAND AG (DE) 2025-03-20 US disclosed
EP-3055344-B1 POLYSILOXANE-POLYCARBONATE BLOCK COCONDENSATES COVESTRO DEUTSCHLAND AG (DE) 2025-03-12 EP disclosed
EP-1612231-A1 Inhibition of catalyst-active impurities in polycarbonate transesterification process Bayer MaterialScience AG (DE) 2006-01-04 EP disclosed
US-20050288407-A1 Thermally stabilized polycarbonate composition BAYER MATERIALSCIENCE AG 2005-12-29 US disclosed
EP-1609818-A2 Heat stabilised polycarbonate compositions Bayer MaterialScience AG (DE) 2005-12-28 EP disclosed
WO-2005103115-A1 PROCESS FOR PRODUCING POLYCARBONATE BAYER MATERIALSCIENCE AG (DE) 2005-11-03 WO disclosed
US-20050239995-A1 Process for the preparation of polycarbonate BAYER MATERIALSCIENCE AG 2005-10-27 US disclosed
WO-2005054335-A1 METHOD FOR PRODUCING POLYCARBONATES HAVING A LOW CONTENT OF VOLATILE COMPOUNDS ACCORDING TO THE TRANSESTERIFICATION PROCESS BAYER MATERIALSCIENCE AG (DE) 2005-06-16 WO disclosed
US-20050131197-A1 Transesterification process for the production of polycarbonates having a low content of volatile compounds COVESTRO DEUTSCHLAND AG (DE) 2005-06-16 US disclosed
EP-0760359-B1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL CO (JP) 1999-10-20 EP disclosed
US-5714627-A REACTING A DIALKYL CARBONATE WITH AN AROMATIC CARBOXYLIC ACID ARYL ESTER IN THE PRESENCE OF A CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1998-02-03 US disclosed
EP-0760359-A1 Method for preparing aromatic carbonate MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1997-03-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12600116-B2 Special polymer layers for faster laminability of multilayer structures ASH2L, SMC2, ELL PTGS2 1779/4885PTGS1 2617/4885CXCR1 4817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.