Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | PYGL | P06737 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971710 | 0.95 | APEX1 (0.37) | APEX1ACHESMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL19971707 | 0.89 | ACHE (0.38) | APEX1ACHESMN1; SMN2KMT2AATM | |
| SCHEMBL25544701 | 0.82 | APEX1 (0.42) | APEX1ACHESMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL1628096 | 0.82 | APEX1 (0.42) | APEX1ACHESMN1; SMN2ZDHHC20ZDHHC2 | |
| Hydrochloric Acid SCHEMBL233973 | 0.80 | APEX1 (0.41) | APEX1ACHESMN1; SMN2ZDHHC20ZDHHC2 | |
| Sulfuric Acid SCHEMBL25230184 | 0.80 | APEX1 (0.42) | APEX1ACHESMN1; SMN2ZDHHC20ZDHHC2 | |
| SCHEMBL20530938 | 0.78 | ACHE (0.50) | APEX1ACHESMN1; SMN2ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL8777430 | 0.77 | ACHE (0.49) | APEX1ACHESMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL22187118 | 0.76 | APEX1 (0.51) | APEX1SMN1; SMN2ZDHHC20ZDHHC2MAPT | |
| SCHEMBL21610956 | 0.74 | APEX1 (0.49) | APEX1SMN1; SMN2ZDHHC20ZDHHC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| EP-4076916-B1 | WETTABLE SILICONE HYDROGEL CONTACT LENSES | ALCON INC (CH) | 2024-06-12 | — | — | EP | claimed |
| EP-4121801-B1 | INSERT MATERIALS WITH HIGH OXYGEN PERMEABILITY AND HIGH REFRACTIVE INDEX | ALCON INC (CH) | 2024-04-17 | — | — | EP | claimed |
| US-11931454-B2 | Wet-packed soft hydrogel ocular inserts | ALCON INC. (CH) | 2024-03-19 | — | — | US | claimed |
| EP-4118134-B1 | PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS | ALCON INC (CH) | 2024-02-28 | — | — | EP | claimed |
| US-11867874-B2 | Insert materials with high oxygen permeability and high refractive index | ALCON INC. (CH) | 2024-01-09 | — | — | US | claimed |
| WO-2023228055-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-30 | — | — | WO | claimed |
| US-20230374306-A1 | UV/HEVL-FILTERING CONTACT LENSES | ALCON INC. (CH) | 2023-11-23 | — | — | US | claimed |
| US-20230364832-A1 | METHOD FOR MAKING UV AND HEVL-ABSORBING OPHTHALMIC LENSES | ALCON INC. (CH) | 2023-11-16 | — | — | US | claimed |
| US-20230357478-A1 | METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2023-11-09 | — | — | US | claimed |
| US-20210181379-A1 | WETTABLE SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2021-06-17 | — | — | US | claimed |
| US-20210132411-A1 | CONTACT LENSES WITH SURFACES HAVING DIFFERENT SOFTNESS | ALCON INC. (CH) | 2021-05-06 | — | — | US | claimed |
| US-10968319-B2 | Silicone hydrogel contact lenses | ALCON INC. (CH) | 2021-04-06 | — | — | US | claimed |
| US-10962803-B2 | Contact lenses with a lubricious coating thereon | ALCON INC. (CH) | 2021-03-30 | — | — | US | claimed |
| WO-2021053586-A1 | WET-PACKED SOFT HYDROGEL OCULAR INSERTS | ALCON INC. (CH) | 2021-03-25 | — | — | WO | claimed |
| US-20210077385-A1 | WET-PACKED SOFT HYDROGEL OCULAR INSERTS | ALCON INC. (CH) | 2021-03-18 | — | — | US | claimed |
| US-20200405747-A1 | OPHTHALMIC COMPOSITIONS | ALCON RESEARCH, LLC | 2020-12-31 | — | — | US | claimed |
| US-20190300654-A1 | METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES | ALCON RESEARCH, LTD. | 2019-10-03 | — | — | US | claimed |
| US-20190263971-A1 | SILICONE HYDROGEL CONTACT LENSES | ALCON INC. (CH) | 2019-08-29 | — | — | US | claimed |
| US-20190235277-A1 | CONTACT LENSES WITH A LUBRICIOUS COATING THEREON | ALCON INC. (CH) | 2019-08-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210077385-A1 | WET-PACKED SOFT HYDROGEL OCULAR INSERTS | BRI3BP, BRWD1, HRH2 | APEX1 2582/4885ACHE 2021/4885SMN1; SMN2 4666/4885 |
| US-11931454-B2 | Wet-packed soft hydrogel ocular inserts | BRI3BP, BRWD1, HRH2 | APEX1 2582/4885ACHE 2021/4885SMN1; SMN2 4666/4885 |
| US-20200405747-A1 | OPHTHALMIC COMPOSITIONS | B4GALT1, B3GAT3, ALG1 | APEX1 1764/4885ACHE 2065/4885SMN1; SMN2 4174/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.