Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CBLB | Q13191 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25544701 | 0.98 | APEX1 (0.42) | APEX1ACHEKMT2AATMSMN1; SMN2 | |
| SCHEMBL1628096 | 0.98 | APEX1 (0.42) | APEX1ACHEKMT2AATMSMN1; SMN2 | |
| Sulfuric Acid SCHEMBL25230184 | 0.91 | APEX1 (0.42) | APEX1ACHEKMT2AATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8777430 | 0.89 | ACHE (0.49) | APEX1ACHEKMT2AATMSMN1; SMN2 | |
| SCHEMBL20530938 | 0.86 | ACHE (0.50) | APEX1ACHEKMT2AATMSMN1; SMN2 | |
| Trifluoromethanesulfonic Acid SCHEMBL25407679 | 0.85 | APEX1 (0.38) | APEX1ACHEKMT2AATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11054825 | 0.84 | KMT2A (0.42) | APEX1KMT2AATMSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL22687484 | 0.82 | APEX1 (0.40) | APEX1KMT2AATMSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3432649 | 0.82 | ACHE (0.38) | ACHEKMT2AATMALDH1A1CBLB | |
| SCHEMBL21610956 | 0.82 | APEX1 (0.49) | APEX1KMT2ASMN1; SMN2ALDH1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 490 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12605326-B2 | Cosmetic composition comprising a polymer comprising at least one cationic (meth)acrylamide unit, a particular silicone and at least one surfactant | L'OREAL (FR) | 2026-04-21 | — | — | US | claimed |
| EP-4171474-A1 | COMPOSITION COMPRISING A PARTICULAR SILICONE EMULSION, A PARTICULAR (METH)ACRYLAMIDE POLYMER, SURFACTANTS AND A CATIONIC POLYSACCHARIDE | L'OREAL (FR) | 2023-05-03 | — | — | EP | claimed |
| US-20230065360-A1 | COSMETIC COMPOSITION COMPRISING A POLYMER COMPRISING AT LEAST ONE CATIONIC (METH)ACRYLAMIDE UNIT, A PARTICULAR SILICONE AND AT LEAST ONE SURFACTANT | L'OREAL (FR) | 2023-03-02 | — | — | US | claimed |
| EP-3647277-A1 | PROCESS FOR DEWATERING AQUEOUS SLUDGE WATER | Clariant International Ltd (CH) | 2020-05-06 | — | — | EP | claimed |
| EP-2720668-B1 | COSMETIC USE OF A FLOCCULANT POLYMER AS ANTIPERSPIRANT | OREAL (FR) | 2020-05-06 | — | — | EP | claimed |
| WO-2018199785-A1 | METHOD FOR PREPARATION OF A LACTOBACILLUS RHAMNOSUS BACTERIAL BIOFILM ON A METAL SURFACE AND BIOELECTRODE OBTAINED BY THIS METHOD | Uniwersytet Jagielloński (PL) | 2018-11-01 | — | — | WO | claimed |
| CN-105102127-B | Ion exchange membrane with specific ion permselectivity | 苏特沃克技术有限公司 | 2018-09-18 | — | — | CN | claimed |
| US-10039706-B2 | Cosmetic composition comprising at least one particular amphoteric polymer and an antidandruff agent | L'OREAL (FR) | 2018-08-07 | — | — | US | claimed |
| EP-2909168-B1 | ACRYLAMIDE-BASED CROSSLINKING MONOMERS, THEIR PREPARATION, AND USES THEREOF | SALTWORKS TECH INC (CA) | 2018-05-09 | — | — | EP | claimed |
| US-9834730-B2 | Use of emulsion polymers to flocculate solids in organic liquids | ECOLAB USA INC. (US) | 2017-12-05 | — | — | US | claimed |
| US-4814101-A | AN ACRYLIC ESTER/AN ACRYLIC ACID/AN ACRYLIC QUATERNARY AMMONIUM COMPOUND TERPOLYMER; POLYAMPHOLYTES; STORAGE STABILITY; SOFTENERS; LONG-LASTING HOLD | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1989-03-21 | — | — | US | claimed |
| US-4734205-A | WATER DISPERSIBLE ACRYLIC PERPOLYMER | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1988-03-29 | — | — | US | claimed |
| EP-0247774-A2 | Cationic monomer delayed addition process | EXXON CHEMICAL PATENTS INC. (US) | 1987-12-02 | — | — | EP | claimed |
| US-4568731-A | ADDING 1,3-DIONE MOIETIES TO ENHANCE PERFORMANCE CHARACTERISTICS AND RATES OF POLYMERIZATION | AMERICAN CYANAMID COMPANY (US) | 1986-02-04 | — | — | US | claimed |
| EP-0049766-B1 | HIGH CONCENTRATION WATER SOLUBLE POLYMERS AS WATER-IN-OIL EMULSIONS | AMERICAN CYANAMID COMPANY (US) | 1985-03-27 | — | — | EP | claimed |
| US-4483959-A | Organic pigments | HERCULES INCORPORATED (US) | 1984-11-20 | — | — | US | claimed |
| US-4404310-A | GRAFT POLYMERS OF UNSATURATED COMPOUND ONTO WATER SOLUBLE CATIONIC POLYMERS | HERCULES INCORPORATED (US) | 1983-09-13 | — | — | US | claimed |
| US-4339371-A | High concentration water-soluble polymers in water-in-oil emulsions | AMERICAN CYANAMID COMPANY (US) | 1982-07-13 | — | — | US | claimed |
| EP-0049766-A1 | High concentration water soluble polymers as water-in-oil emulsions | AMERICAN CYANAMID COMPANY (US) | 1982-04-21 | — | — | EP | claimed |
| US-4311809-A | WATER-INSOLUBLE CATIONIC ADDITION GRAFT POLYMERS; OPAQUE PAPER FILLERS | HERCULES INCORPORATED (US) | 1982-01-19 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10039706-B2 | Cosmetic composition comprising at least one particular amphoteric polymer and an antidandruff agent | ACR, KRT18, ASS1 | ACHE 1997/4885APEX1 382/4885KMT2A 554/4885 |
| US-20230065360-A1 | COSMETIC COMPOSITION COMPRISING A POLYMER COMPRISING AT LEAST ONE CATIONIC (METH)ACRYLAMIDE UNIT, A PARTICULAR SILICONE AND AT LEAST ONE SURFACTANT | KRT18, ACR, MUC1 | ACHE 428/4885APEX1 1732/4885KMT2A 633/4885 |
| US-12605326-B2 | Cosmetic composition comprising a polymer comprising at least one cationic (meth)acrylamide unit, a particular silicone and at least one surfactant | MSH6, KRT18, MMAB | ACHE 1906/4885APEX1 1725/4885KMT2A 1118/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.