Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537093 | 0.83 | NLRP3 (0.61) | KDM4EMAPTNLRP3GAAPOLB | |
| SCHEMBL28299666 | 0.83 | KDM4E (0.62) | KDM4EMAPTGAAPOLBCYP1A2 | |
| SCHEMBL30393282 | 0.81 | KDM4E (0.82) | KDM4EMAPTGAAPOLBCYP1A2 | |
| SCHEMBL1276481 | 0.81 | KDM4E (0.82) | KDM4EMAPTGAAPOLBCYP1A2 | |
| SCHEMBL10780391 | 0.81 | KEAP1 (0.71) | KDM4EMAPTGAACYP1A2KEAP1 | |
| SCHEMBL6465979 | 0.80 | EPHX1 (0.62) | KDM4EMAPTNLRP3GAAPOLB | |
| SCHEMBL6537088 | 0.79 | KDM4E (0.61) | KDM4EMAPTNLRP3GAAPOLB | |
| SCHEMBL11868635 | 0.76 | KDM4E (0.69) | KDM4EMAPTGAAPOLBCYP1A2 | |
| SCHEMBL5187369 | 0.76 | ALDH1A1 (0.77) | KDM4EMAPTNLRP3POLBCYP1A2 | |
| SCHEMBL6468746 | 0.76 | KDM4E (0.51) | KDM4EMAPTNLRP3GAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3274184-B1 | HEAT-SENSITIVE RECORDING MATERIAL | KOEHLER SE AUGUST PAPIERFABRIK (DE) | 2021-05-05 | — | — | EP | claimed |
| US-10265985-B2 | Heat-sensitive recording material | PAPIERFABRIK AUGUST KOEHLER SE (DE) | 2019-04-23 | — | — | US | claimed |
| US-20180079243-A1 | HEAT-SENSITIVE RECORDING MATERIAL | PAPIERFABRIK AUGUST KOEHLER SE (DE) | 2018-03-22 | — | — | US | claimed |
| US-10265985-B2 | Heat-sensitive recording material | PAPIERFABRIK AUGUST KOEHLER SE (DE) | 2019-04-23 | — | — | US | disclosed |
| US-20180079243-A1 | HEAT-SENSITIVE RECORDING MATERIAL | PAPIERFABRIK AUGUST KOEHLER SE (DE) | 2018-03-22 | — | — | US | disclosed |