Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19971762 | 0.83 | KDM4E (0.58) | KDM4EGAAKEAP1RECQLALDH1A1 | |
| SCHEMBL10780391 | 0.82 | KEAP1 (0.71) | KDM4EGAAKEAP1RECQLALDH1A1 | |
| SCHEMBL79802 | 0.77 | KDM4E (1.00) | KDM4EGAAALDH1A1KMT2APOLB | |
| SCHEMBL11793189 | 0.75 | KEAP1 (0.67) | KDM4EGAAKEAP1RECQLALDH1A1 | |
| SCHEMBL45616 | 0.75 | KEAP1 (0.67) | KDM4EGAAKEAP1RECQLALDH1A1 | |
| Hydrogen Sulfide SCHEMBL27471544 | 0.75 | KDM4E (0.96) | KDM4EGAAALDH1A1KMT2APOLB | |
| SCHEMBL4465089 | 0.75 | KEAP1 (0.67) | KDM4EGAAKEAP1RECQLALDH1A1 | |
| SCHEMBL6005274 | 0.75 | KEAP1 (0.71) | KDM4EGAAKEAP1RECQLALDH1A1 | |
| SCHEMBL27515056 | 0.75 | KMT2A (0.62) | KDM4EGAAKEAP1RECQLALDH1A1 | |
| SCHEMBL28781311 | 0.74 | KEAP1 (0.65) | KDM4EGAAKEAP1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107454874-B | Thermal recording medium | 奥古斯特科勒纸厂欧洲公司 | 2019-06-14 | — | — | CN | claimed |