Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL843448 | 0.84 | GAA (0.32) | ADRB2 | |
| SCHEMBL844046 | 0.84 | KCNQ2 (0.35) | KCNQ2ADRA1DADRA1AADRA1BKCNH2 | |
| Hydrochloric Acid SCHEMBL6627934 | 0.81 | PDE4D (0.31) | ADRB2 | |
| Bromide SCHEMBL844917 | 0.81 | PDE4D (0.31) | ADRB2 | |
| SCHEMBL21736891 | 0.78 | CYP11B2 (0.40) | KCNQ2ADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL17185923 | 0.78 | PDXK (0.34) | KCNQ2ADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL31667050 | 0.76 | NOX1 (0.30) | — | |
| SCHEMBL13059147 | 0.74 | BDKRB2 (0.33) | — | |
| SCHEMBL19973149 | 0.74 | CYP11B1 (0.34) | — | |
| SCHEMBL844637 | 0.71 | PDE4D (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018052903-A1 | RORγ MODULATORS | THE SCRIPPS RESEARCH INTITUTE (US) | 2018-03-22 | — | — | WO | disclosed |