Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 2/20 | 0.41 |
| ▸ | PI4KA | P42356 | 2/20 | 0.34 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.34 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL1065182 | 1.00 | MAP4K4 (0.41) | MAP4K4PI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL4579285 | 1.00 | MAP4K4 (0.41) | MAP4K4PI4KAPI4K2BPI4K2API4KB | |
| Guanine SCHEMBL1730016 | 0.89 | DYRK1A (0.42) | MAP4K4LMNAXDHPNPPARP1 | |
| Adenine SCHEMBL4579096 | 0.85 | ATAD2 (0.41) | MAP4K4PNPPARP1 | |
| 2,6-Diaminopurine SCHEMBL23292803 | 0.84 | DYRK1A (0.38) | MAP4K4LMNAPNPDYRK1A | |
| Guanine SCHEMBL2636585 | 0.82 | KDM4E (0.38) | MAP4K4LMNAPNPDYRK1A | |
| Cytosine SCHEMBL15271432 | 0.81 | PNP (0.32) | MAP4K4LRRK2PNPPARP1DYRK1A | |
| Adenine SCHEMBL6227731 | 0.80 | ATAD2 (0.37) | MAP4K4 | |
| Adenine SCHEMBL3416954 | 0.80 | PI4KA (0.48) | MAP4K4PI4KAPI4K2BPI4K2API4KB | |
| Adenine SCHEMBL3414603 | 0.80 | PI4KA (0.48) | MAP4K4PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512860-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB Pharma Inc. (CA) | 2019-07-24 | — | — | EP | claimed |
| WO-2018049534-A1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC. (CA) | 2018-03-22 | — | — | WO | claimed |