Adenine

Adenine

SCHEMBL4579096

Cc1c[nH]c(=O)[nH]c1=O.Nc1cc[nH]c(=O)n1.Nc1ncnc2[nH]cnc12

nearest known ligand 0.41

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.41
MAP4K4 O95819 1/20 0.32
PNP P00491 1/20 0.31
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenine SCHEMBL6227731 0.95 ATAD2 (0.37) ATAD2MAP4K4
Guanine SCHEMBL5097008 0.93 ATAD2 (0.36) ATAD2
Guanine SCHEMBL9468293 0.92 ATAD2 (0.35) ATAD2
Guanine SCHEMBL15718980 0.89 KDM4E (0.33) ATAD2
Acenaphthene SCHEMBL20636762 0.89 ATAD2 (0.33) ATAD2
Adenine SCHEMBL8472509 0.89 ATAD2 (0.53) ATAD2PNPPARP1
Adenine SCHEMBL3474048 0.89 ATAD2 (0.53) ATAD2PNPPARP1
Adenine SCHEMBL4633065 0.89 ATAD2 (0.53) ATAD2PNPPARP1
Guanine SCHEMBL9468221 0.88 KDM4E (0.32) ATAD2
Adenine SCHEMBL4579097 0.85 PI4KA (0.46) ATAD2PNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7319026-B2 Amino acid-producing bacteria and a process for preparing L-amino acids DEGUSSA AG (DE) 2008-01-15 US disclosed
EP-1481075-A2 AMINO ACID-PRODUCING BACTERIA AND A PROCESS FOR PREPARING L-AMINO ACIDS Degussa AG (DE) 2004-12-01 EP disclosed
US-20040082040-A1 Amino acid-producing bacteria and a process for preparing L-amino acids DEGUSSA AG 2004-04-29 US disclosed
WO-2003074719-A2 AMINO ACID-PRODUCING BACTERIA AND A PROCESS FOR PREPARING L-AMINO ACIDS DEGUSSA AG (DE) 2003-09-12 WO disclosed
EP-0986572-A2 IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF Dynavax Technologies Corporation (US) 2000-03-22 EP disclosed
WO-1998055495-A2 IMMUNOSTIMULATORY OLIGONUCLEOTIDES, COMPOSITIONS THEREOF AND METHODS OF USE THEREOF DYNAVAX TECHNOLOGIES CORPORATION (US) 1998-12-10 WO disclosed