Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MASP2 | O00187 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19975405 | 0.87 | MASP2 (0.49) | MASP2RXFP1LMNAKMT2AMEN1 | |
| SCHEMBL19974978 | 0.87 | CTSD (0.44) | MASP2LMNAALDH1A1 | |
| SCHEMBL19974811 | 0.82 | MASP2 (0.47) | MASP2RXFP1LMNAKMT2ASLC2A1 | |
| SCHEMBL19974952 | 0.81 | ALDH1A1 (0.50) | MASP2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL19975435 | 0.81 | MASP2 (0.46) | MASP2RXFP1LMNAKMT2ASLC2A1 | |
| SCHEMBL19975389 | 0.80 | CTSD (0.42) | MASP2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL19975242 | 0.80 | OPRM1 (0.42) | MASP2LMNAALDH1A1 | |
| SCHEMBL19975564 | 0.80 | MASP2 (0.48) | MASP2RXFP1LMNAKMT2AMEN1 | |
| SCHEMBL19975156 | 0.80 | ALDH1A1 (0.54) | LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL21176256 | 0.78 | ALDH1A1 (0.45) | MASP2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512836-A1 | ANTIVIRAL COMPOUNDS | Haplogen GmbH (AT) | 2019-07-24 | — | — | EP | disclosed |
| WO-2018050631-A1 | ANTIVIRAL COMPOUNDS | HAPLOGEN GMBH (AT) | 2018-03-22 | — | — | WO | disclosed |