SCHEMBL19974748

SCHEMBL19974748

CCCC(NC(=O)c1ccccc1)C(=O)C(=O)NC1CC1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 3/20 0.51
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
LMNA P02545 3/20 0.48
RAB9A P51151 3/20 0.48
NPC1 O15118 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.45
HSD17B10 Q99714 1/20 0.45
PRSS1 P07477 1/20 0.44
CTSG P08311 1/20 0.44
CTRB1 P17538 1/20 0.44
CMA1 P23946 1/20 0.44
CAPN1 P07384 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CTSL P07711 2/20 0.43
CTSB P07858 2/20 0.43
CTSS P25774 2/20 0.43
CTSK P43235 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21183566 0.90 MEN1 (0.50) CCR1MEN1KMT2ALMNARAB9A
SCHEMBL19975283 0.82 CCR1 (0.49) CCR1LMNARAB9ANPC1SMN1; SMN2
SCHEMBL14325305 0.81 CTSB (0.52) CAPN1ALDH1A1CTSB
SCHEMBL11936283 0.78 SMN1; SMN2 (0.39) RAB9ASMN1; SMN2ALDH1A1CTSLCTSB
SCHEMBL8236530 0.78 SMN1; SMN2 (0.39) RAB9ASMN1; SMN2ALDH1A1CTSLCTSB
SCHEMBL9829285 0.77 RAB9A (0.60) CCR1MEN1KMT2ALMNARAB9A
SCHEMBL3948327 0.77 RAB9A (0.60) CCR1MEN1KMT2ALMNARAB9A
SCHEMBL24785998 0.77 CTSL (0.51) CAPN1CTSLCTSB
SCHEMBL11985586 0.76 CTSB (0.38) RAB9ASMN1; SMN2ALDH1A1CTSLCTSB
SCHEMBL11985580 0.76 CTSB (0.38) RAB9ASMN1; SMN2ALDH1A1CTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C CCR1 1206/4885MEN1 4331/4885KMT2A 4031/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C CCR1 1694/4885MEN1 4361/4885KMT2A 4177/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C CCR1 1206/4885MEN1 4331/4885KMT2A 4031/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.