SCHEMBL19974941

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19975144	0.89	MAPK14 (0.49)	ALDH1A1SMN1; SMN2RAB9ANPC1MAPK14
	SCHEMBL19975135	0.88	CTSL (0.52)	ALDH1A1SMN1; SMN2NPC1MAPK14F10
	SCHEMBL19975275	0.87	F10 (0.47)	ALDH1A1SMN1; SMN2MAPK14F10PRSS1
	SCHEMBL19975064	0.86	F10 (0.53)	POLBALDH1A1RAB9ANPC1F10
	SCHEMBL28315914	0.85	F10 (0.47)	ALDH1A1MAPK14F10PRSS1ACACB
	SCHEMBL19975354	0.82	ALDH1A1 (0.53)	ALDH1A1SMN1; SMN2MAPK14F10PRSS1
	SCHEMBL19974729	0.82	ALDH1A1 (0.50)	ALDH1A1SMN1; SMN2MAPK14F10PRSS1
	SCHEMBL21183512	0.81	P2RX7 (0.43)	POLBALDH1A1RAB9ANPC1F10
	SCHEMBL21176167	0.81	ALDH1A1 (0.55)	ALDH1A1SMN1; SMN2MEN1KMT2ALMNA
	SCHEMBL19974926	0.81	SMN1; SMN2 (0.47)	POLBALDH1A1SMN1; SMN2RAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.