SCHEMBL19974985

SCHEMBL19974985

COC(=O)CNC(=O)C(O)C(C)NCc1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
PPID Q08752 1/20 0.45
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
HPGD P15428 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA4 P22748 1/20 0.43
CA6 P23280 1/20 0.43
CA5A P35218 1/20 0.43
CA7 P43166 1/20 0.43
CACNA1C Q13936 1/20 0.43
SCN9A Q15858 1/20 0.43
CA9 Q16790 1/20 0.43
CA13 Q8N1Q1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19975169 0.81 KMT2A (0.60) MAPTL3MBTL1KMT2AMEN1HPGD
SCHEMBL20442882 0.81 MAPT (0.54) MAPTL3MBTL1KMT2AMEN1HPGD
SCHEMBL19975268 0.78 PSMB5 (0.48) MAPTL3MBTL1KMT2AMEN1HPGD
SCHEMBL19975037 0.77 SIGMAR1 (0.48) MAPTKMT2AMEN1HPGDTSHR
SCHEMBL11940451 0.77 CYP3A4 (0.63) MAPTKMT2AMEN1HPGDTSHR
SCHEMBL19974746 0.75 MASP2 (0.57) KMT2AMEN1LMNACYP1A2CYP2D6
SCHEMBL19975065 0.75 MDM2 (0.38) KMT2AMEN1HTTLAP3ANPEP
SCHEMBL19975381 0.73 SMN1; SMN2 (0.51) L3MBTL1KMT2AMEN1HPGDSMN1; SMN2
SCHEMBL8996609 0.73 SIGMAR1 (0.56) MAPTL3MBTL1KMT2AMEN1HPGD
SCHEMBL891954 0.73 SIGMAR1 (0.56) MAPTL3MBTL1KMT2AMEN1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220356148-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2022-11-10 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-11091428-B2 Antiviral compounds HAPLOGEN GMBH (AT) 2021-08-17 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
US-20190225575-A1 ANTIVIRAL COMPOUNDS LUNIS CONSULTING GMBH (AT) 2019-07-25 US disclosed
EP-3512836-A1 ANTIVIRAL COMPOUNDS Haplogen GmbH (AT) 2019-07-24 EP disclosed
WO-2018050631-A1 ANTIVIRAL COMPOUNDS HAPLOGEN GMBH (AT) 2018-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190225575-A1 ANTIVIRAL COMPOUNDS PLA2G1B, PLA2G12A, PLA2G4C MAPT 4561/4885L3MBTL1 1238/4885PPID 3660/4885
US-20220356148-A1 ANTIVIRAL COMPOUNDS PLA2G12A, PLA2G1B, PLA2G4C MAPT 4673/4885L3MBTL1 1885/4885PPID 3773/4885
US-11091428-B2 Antiviral compounds PLA2G1B, PLA2G12A, PLA2G4C MAPT 4561/4885L3MBTL1 1238/4885PPID 3660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.