SCHEMBL19975280

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3593402	0.80	ALOX5 (0.74)	ALOX5RAB9ANPC1SMN1; SMN2PDPK1
	SCHEMBL25666864	0.79	ALOX5 (0.57)	ALOX5RAB9ANPC1ALDH1A1LMNA
	SCHEMBL8321281	0.77	ALOX5 (0.65)	ALOX5RAB9ANPC1ALDH1A1LMNA
	SCHEMBL6752	0.73	ALDH1A1 (0.63)	ALOX5ALDH1A1LMNAMAPTGAA
	SCHEMBL2238148	0.73	ALDH1A1 (0.69)	ALOX5NPC1ALDH1A1LMNACA12
	SCHEMBL29901720	0.73	ALDH1A1 (0.63)	ALOX5ALDH1A1LMNAMAPTGAA
	SCHEMBL21273284	0.72	ALDH1A1 (0.45)	ALOX5RAB9ANPC1ALDH1A1LMNA
	SCHEMBL31750319	0.72	SMYD3 (0.59)	ALOX5ALDH1A1LMNAHSD17B10GAA
	SCHEMBL2238303	0.72	SMYD3 (0.59)	ALOX5ALDH1A1LMNAHSD17B10GAA
	SCHEMBL12362558	0.72	SMYD3 (0.59)	ALOX5ALDH1A1LMNAHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.