Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.84 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.74 |
| ▸ | GFER | P55789 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 1/20 | 0.52 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.50 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92507 | 0.92 | SMN1; SMN2 (0.82) | MAPTSMN1; SMN2GFERL3MBTL1SIGMAR1 | |
| SCHEMBL9321597 | 0.92 | MAPT (1.00) | MAPTSMN1; SMN2GFERL3MBTL1SIGMAR1 | |
| SCHEMBL19975593 | 0.81 | MAPT (0.78) | MAPTSMN1; SMN2GFERL3MBTL1SIGMAR1 | |
| SCHEMBL3673014 | 0.80 | SMN1; SMN2 (0.58) | MAPTSMN1; SMN2GFERL3MBTL1SIGMAR1 | |
| SCHEMBL2236750 | 0.79 | SMN1; SMN2 (0.84) | MAPTSMN1; SMN2GFERL3MBTL1SIGMAR1 | |
| SCHEMBL13068565 | 0.77 | FKBP1A (0.60) | MAPTSMN1; SMN2SIGMAR1HPGDALDH1A1 | |
| SCHEMBL654109 | 0.76 | TPSAB1 (0.76) | MAPTSMN1; SMN2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL31499419 | 0.76 | SMN1; SMN2 (0.79) | MAPTSMN1; SMN2GFERL3MBTL1HPGD | |
| SCHEMBL31499420 | 0.76 | SMN1; SMN2 (0.79) | MAPTSMN1; SMN2GFERL3MBTL1HPGD | |
| SCHEMBL31499418 | 0.76 | SMN1; SMN2 (0.79) | MAPTSMN1; SMN2GFERL3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920082-B2 | Water-soluble complexing agents and corresponding lanthanide complexes | CISBO BIOASSAYS (FR) | 2018-03-20 | — | — | US | disclosed |