SCHEMBL19976715

SCHEMBL19976715

NN1CN(N)c2ncccc21

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.34
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
GRIN1 Q05586 1/20 0.33
GRIN2A Q12879 1/20 0.33
GRIN2B Q13224 1/20 0.33
GRIN2C Q14957 1/20 0.33
GRIN3A Q8TCU5 1/20 0.33
HTR2C P28335 2/20 0.33
HTR3E A5X5Y0 1/20 0.33
HTR3B O95264 1/20 0.33
HTR1A P08908 1/20 0.33
HTR3A P46098 1/20 0.33
HTR3D Q70Z44 1/20 0.33
HTR3C Q8WXA8 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24981938 0.76 NOS3 (0.42) ALDH1A1KMT2AHSD11B1LMNASMN1; SMN2
SCHEMBL19976713 0.71 KEAP1 (0.36) ALDH1A1MAPTMEN1KMT2AADRA2C
SCHEMBL27973984 0.69 NOS3 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL178982 0.67 GAA (0.45) EPHX2ALDH1A1MAPTL3MBTL1ADRA2A
SCHEMBL13068413 0.65 GRIN2D (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL12642490 0.64
SCHEMBL8101449 0.64 MYC (0.40) EPHX2L3MBTL1MEN1KMT2AADRA2A
SCHEMBL24342186 0.64 GAA (0.47) EPHX2MAPTLMNASMN1; SMN2
SCHEMBL24158353 0.64 ADRA2A (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10777910 0.63 GRIA2 (0.45) EPHX2HTR2CHTR3EHTR3BHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9919288-B2 ZIF-containing adsorbent materials and uses thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2018-03-20 US disclosed