Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 6/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.43 |
| ▸ | MAP2K4 | P45985 | 6/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.39 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976820 | 0.90 | HDAC6 (0.46) | GSK3BGSK3AMAP2K4HDAC6CYP1A2 | |
| SCHEMBL19976747 | 0.89 | GSK3B (0.45) | GSK3BAAK1GSK3AFGFR1FGFR2 | |
| SCHEMBL19976859 | 0.87 | GSK3B (0.45) | GSK3BAAK1GSK3AFGFR1FGFR2 | |
| SCHEMBL16769266 | 0.84 | GSK3B (0.46) | GSK3BAAK1GSK3AFGFR1FGFR2 | |
| SCHEMBL16752862 | 0.84 | GSK3B (0.46) | GSK3BAAK1GSK3AFGFR1FGFR2 | |
| SCHEMBL16752864 | 0.84 | GSK3B (0.46) | GSK3BAAK1GSK3AFGFR1FGFR2 | |
| SCHEMBL19976765 | 0.79 | NTRK1 (0.41) | GSK3BGSK3AMAP2K4HDAC6CYP1A2 | |
| SCHEMBL18558410 | 0.78 | CA12 (0.37) | HDAC6ANO1 | |
| SCHEMBL19976730 | 0.78 | HDAC6 (0.41) | GSK3BGSK3AFGFR1FGFR2FGFR3 | |
| SCHEMBL19976787 | 0.78 | HDAC6 (0.43) | GSK3BGSK3AFGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |