Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 10/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 2/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | LYN | P07948 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976875 | 0.87 | HDAC6 (0.35) | MAPK1HDAC6ABL1BCRGSK3B | |
| SCHEMBL19976764 | 0.85 | GSK3B (0.48) | MAPK1HDAC6GSK3BCYP1A2FGFR1 | |
| SCHEMBL19976758 | 0.85 | DYRK1A (0.40) | MAPK1HDAC6ABL1BCRHPGD | |
| SCHEMBL19976731 | 0.82 | MAPK1 (0.42) | MAPK1HDAC6ABL1BCRGSK3B | |
| SCHEMBL19976858 | 0.82 | MAPK1 (0.46) | MAPK1HDAC6ABL1BCRGSK3B | |
| SCHEMBL19976849 | 0.82 | HDAC6 (0.36) | MAPK1HDAC6ABL1BCRKDR | |
| SCHEMBL19976812 | 0.80 | GSK3B (0.51) | MAPK1HDAC6GSK3BFGFR1FGFR2 | |
| SCHEMBL19976815 | 0.79 | GSK3B (0.44) | MAPK1HDAC6GSK3BKITFLT4 | |
| SCHEMBL19976768 | 0.78 | MAPK1 (0.38) | MAPK1HDAC6ABL1BCRGSK3B | |
| SCHEMBL19976907 | 0.78 | GSK3B (0.49) | MAPK1HDAC6ABL1BCRGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |