Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 5/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | LYN | P07948 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | FLT4 | P35916 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | BLK | P51451 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976802 | 0.92 | KDR (0.36) | KDRLCKFYNCSF1RLYN | |
| SCHEMBL19976875 | 0.89 | HDAC6 (0.35) | HDAC6KDRLCKFYNCSF1R | |
| SCHEMBL19976758 | 0.85 | DYRK1A (0.40) | HDAC6KDRLCKFYNCSF1R | |
| SCHEMBL19976726 | 0.83 | ABL1 (0.41) | HDAC6KDRLCKFYNCSF1R | |
| SCHEMBL19976877 | 0.82 | MAPK1 (0.40) | HDAC6KDRLCKFYNCSF1R | |
| SCHEMBL19976730 | 0.80 | HDAC6 (0.41) | HDAC6FLT4JAK2MAPK1 | |
| SCHEMBL16752857 | 0.79 | CHRNA1 (0.34) | KCNQ3KCNQ2JAK2CHRNA1CHRNG | |
| SCHEMBL16752855 | 0.79 | CHRNA1 (0.34) | KCNQ3KCNQ2JAK2CHRNA1CHRNG | |
| SCHEMBL19976765 | 0.79 | NTRK1 (0.41) | HDAC6LCKFLT4FLT3JAK2 | |
| SCHEMBL18558420 | 0.79 | MEN1 (0.36) | HDAC6FYNHTTKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |