Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.34 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 4/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | LYN | P07948 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | FLT4 | P35916 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
| ▸ | BLK | P51451 | 1/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.32 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976849 | 0.89 | HDAC6 (0.36) | HDAC6MAPK1MAPK3ABL1BCR | |
| SCHEMBL19976758 | 0.88 | DYRK1A (0.40) | HDAC6MAPK1MAPK3ABL1BCR | |
| SCHEMBL19976877 | 0.87 | MAPK1 (0.40) | HDAC6MAPK1MAPK3ABL1BCR | |
| SCHEMBL19976757 | 0.81 | HDAC6 (0.39) | HDAC6ABL1BCRFLT4FLT3 | |
| SCHEMBL19976802 | 0.80 | KDR (0.36) | MAPK1ABL1BCRKDRLCK | |
| SCHEMBL19976800 | 0.78 | GSK3B (0.43) | HDAC6MAPK1FLT4GSK3B | |
| SCHEMBL18558427 | 0.77 | KCNQ3 (0.35) | ABL1BCRKCNQ3KCNQ2KCNQ5 | |
| SCHEMBL9920876 | 0.75 | LMNA (0.33) | ABL1BCRKCNQ3KCNQ2KCNQ5 | |
| SCHEMBL9920898 | 0.75 | PRKAB2 (0.39) | MAPK1ABL1BCR | |
| SCHEMBL19976886 | 0.74 | GSK3B (0.43) | HDAC6MAPK1CYP1A2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9920012-B2 | Indazole guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2018-03-20 | — | — | US | disclosed |