Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976952 | 0.90 | APLNR (0.57) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL19977059 | 0.88 | KMT2A (0.58) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL19977006 | 0.87 | APLNR (0.54) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL17295044 | 0.84 | APLNR (1.00) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL19976901 | 0.84 | GAA (0.59) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL16994063 | 0.83 | APLNR (0.65) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL19976980 | 0.81 | NPC1 (0.66) | MAPTKMT2AMEN1POLBALDH1A1 | |
| SCHEMBL25080539 | 0.80 | APLNR (0.61) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL18261133 | 0.80 | APLNR (0.61) | APLNRMAPTSMN1; SMN2GAAKMT2A | |
| SCHEMBL16999271 | 0.80 | APLNR (0.61) | APLNRMAPTSMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |