Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976931 | 0.87 | APLNR (0.72) | APLNRKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL16993910 | 0.83 | HSPA5 (0.59) | APLNRKMT2AMEN1ATMSMN1; SMN2 | |
| SCHEMBL19976893 | 0.82 | SMN1; SMN2 (0.60) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL19976901 | 0.81 | GAA (0.59) | APLNRKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL19976952 | 0.80 | APLNR (0.57) | APLNRKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL19977035 | 0.79 | KMT2A (0.61) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL19976916 | 0.79 | KMT2A (0.51) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL19977046 | 0.78 | KMT2A (0.50) | KMT2AMEN1SMN1; SMN2HTTRAB9A | |
| SCHEMBL19977059 | 0.78 | KMT2A (0.58) | APLNRKMT2AMEN1SMN1; SMN2RAB9A | |
| SCHEMBL19976982 | 0.76 | L3MBTL1 (0.52) | KMT2AMEN1SMN1; SMN2HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |