Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976982 | 0.84 | L3MBTL1 (0.52) | GAAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL19976948 | 0.84 | KMT2A (0.58) | GAAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL19976931 | 0.84 | APLNR (0.72) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL7991476 | 0.83 | MAPT (0.68) | GAAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL19977006 | 0.81 | APLNR (0.54) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19976952 | 0.81 | APLNR (0.57) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19977040 | 0.80 | MAPT (0.71) | GAAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL19976947 | 0.80 | MEN1 (0.53) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL19976994 | 0.79 | PGR (0.57) | GAAMEN1KMT2ANPSR1MAPT | |
| SCHEMBL19976922 | 0.79 | HPGD (0.66) | GAAMAPTALDH1A1HSD17B10PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |