Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | APLNR | P35414 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976931 | 0.88 | APLNR (0.72) | KMT2AMEN1L3MBTL1APLNRPOLB | |
| SCHEMBL19976982 | 0.85 | L3MBTL1 (0.52) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL16993869 | 0.82 | KMT2A (0.51) | KMT2AMEN1L3MBTL1APLNRPOLB | |
| SCHEMBL19976952 | 0.82 | APLNR (0.57) | KMT2AMEN1L3MBTL1APLNRPOLB | |
| SCHEMBL19976942 | 0.82 | MEN1 (0.52) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL19977009 | 0.80 | KMT2A (0.53) | KMT2AMEN1POLBALDH1A1MAPT | |
| SCHEMBL19976930 | 0.79 | ALDH1A1 (0.55) | KMT2AMEN1L3MBTL1POLBALDH1A1 | |
| SCHEMBL19977006 | 0.78 | APLNR (0.54) | KMT2AMEN1APLNRALDH1A1MAPT | |
| SCHEMBL19977007 | 0.77 | KMT2A (0.58) | KMT2AMEN1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL19976936 | 0.77 | SRPK1 (0.48) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |