Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977056 | 0.90 | KDM4E (0.59) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19976959 | 0.88 | LMNA (0.59) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19977129 | 0.87 | ALDH1A1 (0.57) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19977105 | 0.85 | ALDH1A1 (0.55) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19977055 | 0.84 | POLB (0.61) | LMNAALDH1A1SMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL16993888 | 0.83 | ALDH1A1 (0.55) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL16999343 | 0.81 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL16993882 | 0.81 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL19977098 | 0.81 | KDM4E (0.51) | LMNAALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL19976917 | 0.80 | ALDH1A1 (0.66) | LMNAALDH1A1MAPTL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |