Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977056 | 0.91 | KDM4E (0.59) | KDM4EHTTMAPTCYP3A4CYP2D6 | |
| SCHEMBL19977130 | 0.89 | L3MBTL1 (0.44) | KDM4EHTTMAPTCYP3A4CYP2D6 | |
| SCHEMBL19976959 | 0.88 | LMNA (0.59) | KDM4EHTTMAPTLMNAMEN1 | |
| SCHEMBL19976996 | 0.87 | LMNA (0.53) | KDM4EHTTMAPTLMNAMEN1 | |
| SCHEMBL16994064 | 0.86 | KDM4E (0.47) | KDM4EHTTMAPTCYP3A4CYP2D6 | |
| SCHEMBL16999844 | 0.86 | KDM4E (0.47) | KDM4EHTTMAPTCYP3A4CYP2D6 | |
| SCHEMBL19977007 | 0.82 | KMT2A (0.58) | KDM4EHTTMAPTLMNAMEN1 | |
| SCHEMBL19976919 | 0.81 | LMNA (0.47) | KDM4EHTTMAPTLMNAMEN1 | |
| SCHEMBL19976960 | 0.81 | LMNA (0.58) | KDM4EHTTMAPTLMNAMEN1 | |
| SCHEMBL19977012 | 0.80 | ALDH1A1 (0.46) | KDM4EHTTMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |