Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.57 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977082 | 0.89 | KCNQ2 (0.65) | POLBALDH1A1KCNQ2KMT2AMEN1 | |
| SCHEMBL19977048 | 0.88 | KCNQ2 (0.64) | POLBALDH1A1KCNQ2KMT2AMEN1 | |
| SCHEMBL19976996 | 0.87 | LMNA (0.53) | POLBALDH1A1TSHRKMT2AMEN1 | |
| SCHEMBL19977050 | 0.87 | MAPK1 (0.63) | POLBALDH1A1KCNQ2TSHRKMT2A | |
| SCHEMBL19977049 | 0.86 | ALDH1A1 (0.55) | POLBALDH1A1KCNQ2TSHRKMT2A | |
| SCHEMBL19976934 | 0.86 | ALDH1A1 (0.64) | POLBALDH1A1KCNQ2TSHRKMT2A | |
| SCHEMBL19976959 | 0.85 | LMNA (0.59) | POLBALDH1A1KCNQ2TSHRKMT2A | |
| SCHEMBL19976960 | 0.84 | LMNA (0.58) | POLBALDH1A1KCNQ2TSHRKMT2A | |
| SCHEMBL19976917 | 0.84 | ALDH1A1 (0.66) | POLBALDH1A1KCNQ2TSHRKMT2A | |
| SCHEMBL19977058 | 0.83 | ALDH1A1 (0.60) | POLBALDH1A1KCNQ2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |