Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16994058 | 0.82 | USP30 (0.51) | HSPA5HSPA9KMT2A | |
| SCHEMBL16999546 | 0.82 | USP30 (0.51) | HSPA5HSPA9KMT2A | |
| SCHEMBL19976938 | 0.81 | SMN1; SMN2 (0.51) | SMN1; SMN2HSPA5HSPA9HTTLMNA | |
| SCHEMBL19977087 | 0.79 | SMN1; SMN2 (0.50) | SMN1; SMN2HSPA5HSPA9HTTLMNA | |
| SCHEMBL19976894 | 0.78 | ALDH1A1 (0.62) | SMN1; SMN2HTTLMNAL3MBTL1MEN1 | |
| SCHEMBL19977057 | 0.77 | SMN1; SMN2 (0.46) | SMN1; SMN2HSPA5HSPA9LMNAGFER | |
| SCHEMBL19977125 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2HSPA5HSPA9HTTLMNA | |
| SCHEMBL19977000 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2HSPA5HSPA9LMNAGFER | |
| SCHEMBL21812088 | 0.75 | MCL1 (0.39) | SMN1; SMN2LMNAMEN1KMT2AALDH1A1 | |
| SCHEMBL19976922 | 0.74 | HPGD (0.66) | SMN1; SMN2HTTLMNAGFERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |