Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | HSPA9 | P38646 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | NT5C2 | P49902 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976997 | 0.85 | MAPT (0.41) | LMNANPC1RAB9AMAPT | |
| SCHEMBL19977103 | 0.84 | KMT2A (0.46) | SMN1; SMN2LMNANPC1RAB9AMAPT | |
| SCHEMBL16993957 | 0.82 | USP30 (0.51) | — | |
| SCHEMBL16999822 | 0.82 | USP30 (0.51) | — | |
| SCHEMBL19976902 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAGFERGPR139NPC1 | |
| SCHEMBL19976894 | 0.78 | ALDH1A1 (0.62) | SMN1; SMN2LMNACYP3A4MAPT | |
| SCHEMBL19976965 | 0.77 | SMN1; SMN2 (0.51) | SMN1; SMN2LMNAGFERGPR139HSPA5 | |
| SCHEMBL19976900 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAGFERNPC1RAB9A | |
| SCHEMBL19976958 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAGFERHSPA5HSPA9 | |
| SCHEMBL19977125 | 0.76 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNAGFERHSPA5HSPA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |