Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.57 |
| ▸ | EIF4H | Q15056 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976939 | 0.85 | ALDH1A1 (0.56) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL19977004 | 0.84 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL19976908 | 0.84 | ALDH1A1 (0.55) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL19976933 | 0.84 | PABPC1 (0.73) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL19977125 | 0.84 | SMN1; SMN2 (0.45) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL995824 | 0.83 | HDAC6 (0.79) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL19976958 | 0.83 | SMN1; SMN2 (0.56) | ALDH1A1MEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL19977039 | 0.82 | KDR (0.70) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL16999330 | 0.82 | USP30 (0.59) | ALDH1A1KDM4EHDAC6MEN1KMT2A | |
| SCHEMBL16994008 | 0.82 | USP30 (0.59) | ALDH1A1KDM4EHDAC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |