Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976967 | 0.88 | RAB9A (0.43) | LMNAGAAHSD17B10MEN1KMT2A | |
| SCHEMBL19977101 | 0.86 | SMN1; SMN2 (0.43) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL16994031 | 0.84 | MMP2 (0.49) | MAPT | |
| SCHEMBL19976994 | 0.79 | PGR (0.57) | PGRSCN1ASCN2ASCN3AMAPT | |
| SCHEMBL19976966 | 0.77 | TRPV1 (0.46) | KMT2ARAB9ANPC1 | |
| SCHEMBL19976939 | 0.76 | ALDH1A1 (0.56) | MAPTLMNAHPGDHSD17B10MEN1 | |
| SCHEMBL19976997 | 0.75 | MAPT (0.41) | PGRSCN1ASCN2ASCN3AMAPT | |
| SCHEMBL16994035 | 0.73 | CTSL (0.49) | — | |
| SCHEMBL19976963 | 0.73 | TRPV1 (0.56) | LMNAHPGDCYP1A2CYP2C19NPSR1 | |
| SCHEMBL19977032 | 0.72 | MAPT (0.55) | MAPTGAAHPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |