Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976899 | 0.86 | KMT2A (0.49) | GAANPC1RAB9AKMT2AKDM4E | |
| SCHEMBL16999308 | 0.84 | GAA (0.55) | GAANPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL19976980 | 0.83 | NPC1 (0.66) | NPC1RAB9AKMT2ALMNAALDH1A1 | |
| SCHEMBL19976971 | 0.82 | HDAC1 (0.53) | NPC1RAB9AKMT2AKDM4EL3MBTL1 | |
| SCHEMBL19977138 | 0.81 | HPGD (0.48) | GAARAB9AKMT2AL3MBTL1LMNA | |
| SCHEMBL19976893 | 0.80 | SMN1; SMN2 (0.60) | NPC1RAB9AKMT2AHTTTSHR | |
| SCHEMBL19977069 | 0.79 | ALDH1A1 (0.57) | RAB9AL3MBTL1LMNAALDH1A1MAPT | |
| SCHEMBL16119627 | 0.78 | EPHX1 (0.62) | GAANPC1RAB9AKMT2AKDM4E | |
| SCHEMBL19976970 | 0.77 | NPC1 (0.53) | NPC1RAB9AKMT2ALMNAALDH1A1 | |
| SCHEMBL19976922 | 0.76 | HPGD (0.66) | GAANPC1RAB9AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |