Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | UBE2N | P61088 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19976972 | 0.86 | GAA (0.59) | KMT2AKDM4EL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL19976980 | 0.84 | NPC1 (0.66) | KMT2AALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL19976893 | 0.84 | SMN1; SMN2 (0.60) | KMT2ARAB9ANPC1MEN1SMN1; SMN2 | |
| SCHEMBL19976971 | 0.83 | HDAC1 (0.53) | KMT2AKDM4EL3MBTL1RAB9ANPC1 | |
| SCHEMBL16994021 | 0.82 | CTSL (0.52) | KMT2A | |
| SCHEMBL19977124 | 0.79 | SMN1; SMN2 (0.62) | KMT2AALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL23593886 | 0.78 | CTSL (0.55) | KMT2AALDH1A1LMNANPSR1MAPT | |
| SCHEMBL19977069 | 0.78 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL19976970 | 0.78 | NPC1 (0.53) | KMT2AALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL19976922 | 0.77 | HPGD (0.66) | KDM4EALDH1A1RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |