Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977056 | 0.88 | KDM4E (0.59) | LMNAALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL19976987 | 0.88 | ALDH1A1 (0.45) | LMNAALDH1A1SMN1; SMN2TSHRKDM4E | |
| SCHEMBL19977098 | 0.87 | KDM4E (0.51) | LMNAALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL19977055 | 0.87 | POLB (0.61) | LMNAALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL19977007 | 0.84 | KMT2A (0.58) | LMNAALDH1A1SMN1; SMN2KDM4ENPSR1 | |
| SCHEMBL16993923 | 0.84 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL19976950 | 0.78 | ALDH1A1 (0.51) | LMNAALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL19976960 | 0.77 | LMNA (0.58) | LMNAALDH1A1SMN1; SMN2POLBTSHR | |
| SCHEMBL19977082 | 0.77 | KCNQ2 (0.65) | LMNAALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL16993939 | 0.76 | ALDH1A1 (0.50) | LMNAALDH1A1SMN1; SMN2POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |