Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PYGL | P06737 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19977103 | 0.88 | KMT2A (0.46) | MAPTHSD17B10HTTKDM4ELMNA | |
| SCHEMBL19977057 | 0.85 | SMN1; SMN2 (0.46) | MAPTLMNANPC1RAB9A | |
| SCHEMBL16994047 | 0.84 | MMP2 (0.47) | L3MBTL1 | |
| SCHEMBL19977034 | 0.80 | PARP1 (0.46) | MAPTHSD17B10PARP1HTTKDM4E | |
| SCHEMBL19976994 | 0.80 | PGR (0.57) | MAPTHSD17B10HTTKDM4ELMNA | |
| SCHEMBL19976939 | 0.79 | ALDH1A1 (0.56) | MAPTHSD17B10HTTKDM4ELMNA | |
| SCHEMBL24862983 | 0.78 | KDM4E (0.43) | MAPTHSD17B10HTTKDM4EKMT2A | |
| SCHEMBL19976941 | 0.75 | PGR (0.40) | MAPTHSD17B10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19976963 | 0.74 | TRPV1 (0.56) | CYP1A2CYP2C19HTTLMNANPSR1 | |
| SCHEMBL19977032 | 0.73 | MAPT (0.55) | MAPTHSD17B10HTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9919998-B2 | Antibacterial agents: Nα-aroyl-N-aryl-phenylalaninamides | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2018-03-20 | — | — | US | disclosed |