Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6429098 | 0.86 | SMN1; SMN2 (0.54) | KAT2BTSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL28390299 | 0.83 | PAOX (0.53) | PAOXTSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL15920926 | 0.81 | HRH3 (0.54) | PAOXTSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL20179502 | 0.81 | HRH3 (0.54) | PAOXTSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL13943130 | 0.81 | PAOX (0.56) | PAOXKAT2BTSHRSMN1; SMN2LMNA | |
| SCHEMBL28909534 | 0.81 | KAT2B (0.42) | PAOXKAT2BTSHRSMN1; SMN2BRD4 | |
| SCHEMBL25751543 | 0.81 | TSHR (0.52) | PAOXKAT2BTSHRSMN1; SMN2LMNA | |
| SCHEMBL9856869 | 0.80 | SMN1; SMN2 (0.53) | PAOXTSHRSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9293161 | 0.79 | PAOX (0.49) | PAOXKAT2BTSHRSMN1; SMN2LMNA | |
| SCHEMBL11570934 | 0.79 | TSHR (0.58) | PAOXKAT2BTSHRSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) | 2021-02-11 | — | — | US | disclosed |
| US-10633542-B2 | Azacyanine dyes and use thereof | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2020-04-28 | — | — | US | disclosed |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INTRACE MEDICAL SA (CH) | 2019-09-26 | — | — | US | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | Ecole polytechnique fédérale de Lausanne (EPFL) (CH) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210040326-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | PAOX 4599/4885KAT2B 1627/4885TSHR 2336/4885 |
| US-20190292371-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | PAOX 4599/4885KAT2B 1627/4885TSHR 2336/4885 |
| US-10633542-B2 | Azacyanine dyes and use thereof | INMT, AZI2, MYADM | PAOX 4599/4885KAT2B 1627/4885TSHR 2336/4885 |
| US-20180079906-A1 | AZACYANINE DYES AND USE THEREOF | INMT, AZI2, MYADM | PAOX 4599/4885KAT2B 1627/4885TSHR 2336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.