SCHEMBL19978490

SCHEMBL19978490

c1ccc2cc(-c3ccc(-c4ccc5c(-c6ccc7ccccc7c6)c6ccccc6c(-c6ccc7ccccc7c6)c5c4)cn3)ccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 3/20 0.44
CYP11B2 P19099 3/20 0.44
CYP17A1 P05093 1/20 0.44
CYP19A1 P11511 1/20 0.44
HSD17B1 P14061 1/20 0.43
HSD17B2 P37059 1/20 0.43
CYP1A2 P05177 3/20 0.41
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
CYP2C19 P33261 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
AR P10275 1/20 0.39
MAPT P10636 1/20 0.39
NFKB1 P19838 1/20 0.39
RAB9A P51151 1/20 0.39
GFER P55789 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12571838 0.96 CYP11B1 (0.43) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL12322257 0.95 CYP11B1 (0.45) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL15977762 0.94 CYP11B1 (0.45) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL15977420 0.94 CYP1A1 (0.43) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL15977545 0.93 CYP11B1 (0.44) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL15977474 0.93 CYP11B1 (0.44) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL21249207 0.92 CYP11B1 (0.45) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL13147143 0.92 CYP11B1 (0.42) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL12436005 0.92 CYP11B1 (0.45) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1
SCHEMBL17680014 0.91 CYP11B1 (0.46) CYP11B1CYP11B2CYP17A1CYP19A1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230045531-A1 NOVEL ORGANOMETALLIC COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME SFC CO., LTD. (KR) 2023-02-09 US disclosed
US-20220093880-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2022-03-24 US disclosed
US-20180158881-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180158881-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-07 US disclosed
US-20180083196-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed
US-20180083196-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230045531-A1 NOVEL ORGANOMETALLIC COMPOUNDS AND ORGANIC LIGHT EMITTING DIODE INCLUDING SAME ODC1, ORMDL3, ALDH1A2 CYP11B1 172/4885CYP11B2 192/4885CYP17A1 894/4885
US-20220093880-A1 ORGANOMETALLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, LEF1, POU2F1 CYP11B1 766/4885CYP11B2 1002/4885CYP17A1 1111/4885
US-20180083196-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 CYP11B1 543/4885CYP11B2 737/4885CYP17A1 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.