Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SPR | P35270 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12590064 | 0.88 | HTT (0.37) | HTTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL16309339 | 0.84 | MTNR1A (0.46) | SMN1; SMN2LMNAL3MBTL1HDAC3HDAC4 | |
| SCHEMBL13950300 | 0.84 | SMN1; SMN2 (0.40) | HTTSMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL13225533 | 0.84 | SMN1; SMN2 (0.49) | HTTSMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL18471059 | 0.83 | HDAC6 (0.34) | HTTSMN1; SMN2HPGDLMNAL3MBTL1 | |
| SCHEMBL13226737 | 0.83 | SMN1; SMN2 (0.41) | HTTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL15934066 | 0.81 | MTNR1A (0.41) | HTTSMN1; SMN2HPGDALDH1A1KDM4E | |
| SCHEMBL18557387 | 0.81 | SMN1; SMN2 (0.46) | SMN1; SMN2HPGDALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL20330624 | 0.81 | HPGD (0.36) | HTTSMN1; SMN2HPGDALDH1A1LMNA | |
| SCHEMBL12590065 | 0.80 | AKT1 (0.34) | HTTSMN1; SMN2ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180080058-A1 | NANOPATTERNED EXTRACELLULAR MATRICES ENABLE CELL-BASED ASSAYS WITH A MASS SPECTROMETRIC READOUT | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-22 | — | — | US | disclosed |