Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16307671 | 0.85 | TP53 (0.48) | SMN1; SMN2TP53HDAC3HDAC4HDAC1 | |
| SCHEMBL16309339 | 0.84 | MTNR1A (0.46) | SMN1; SMN2TP53HDAC3HDAC4HDAC1 | |
| SCHEMBL18471059 | 0.83 | HDAC6 (0.34) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13531993 | 0.83 | HDAC3 (0.38) | SMN1; SMN2TP53HDAC3HDAC4HDAC1 | |
| SCHEMBL20465783 | 0.83 | SMN1; SMN2 (0.43) | SMN1; SMN2TP53HDAC3HDAC4HDAC1 | |
| SCHEMBL18557296 | 0.81 | LMNA (0.44) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15934066 | 0.81 | MTNR1A (0.41) | SMN1; SMN2TP53KMT2AHPGDALDH1A1 | |
| SCHEMBL19978666 | 0.81 | HTT (0.39) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20330624 | 0.81 | HPGD (0.36) | SMN1; SMN2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15934070 | 0.80 | KMT2A (0.35) | SMN1; SMN2TP53HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9579367-B2 | C-terminally tethered amino acids and their fibrinolytic therapeutic uses | CANADIAN BLOOD SERVICES (CA) | 2017-02-28 | — | — | US | disclosed |