Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980105 | 0.81 | MAPT (0.44) | KDM4EHSD17B10TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL19980217 | 0.77 | GAA (0.38) | KDM4EHSD17B10TSHRMAPK1ALDH1A1 | |
| SCHEMBL19980189 | 0.76 | F9 (0.38) | TAS2R14MAPTGAAHCRTR1HCRTR2 | |
| SCHEMBL19980213 | 0.75 | POLB (0.44) | KDM4EHSD17B10TSHRMAPK1ALDH1A1 | |
| SCHEMBL19980104 | 0.75 | KDM4E (0.39) | KDM4ETSHRALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL1671670 | 0.75 | HCRTR1 (0.50) | TAS2R14CYP1A2CYP2C9CYP2C19HCRTR1 | |
| SCHEMBL19980223 | 0.75 | ALDH1A1 (0.36) | KDM4EHSD17B10TSHRMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1827340 | 0.74 | STING1 (0.43) | KDM4EHSD17B10TSHRMAPK1ALDH1A1 | |
| SCHEMBL19980109 | 0.73 | NPC1 (0.40) | KDM4EHSD17B10TSHRMAPK1ALDH1A1 | |
| SCHEMBL8180740 | 0.73 | MAPK10 (0.43) | KDM4EALDH1A1SMN1; SMN2HPGDSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |