Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | CD38 | P28907 | 8/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | F9 | P00740 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.31 |
| ▸ | TUBB | P07437 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980223 | 0.82 | ALDH1A1 (0.36) | CYP1A2CYP2C19SCN10ALMNAMAPT | |
| SCHEMBL19979964 | 0.82 | SCN10A (0.36) | SCN10ALMNATP53 | |
| SCHEMBL19979960 | 0.78 | TUBB4A (0.38) | TRPV1LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL19979969 | 0.78 | SMN1; SMN2 (0.37) | SCN10ALMNAMAPTALDH1A1TP53 | |
| SCHEMBL19979876 | 0.77 | TUBB4A (0.35) | SCN10ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19980132 | 0.71 | POLB (0.44) | TRPV1CD38CYP1A2CYP2C19SCN10A | |
| SCHEMBL19979956 | 0.70 | ALDH1A1 (0.33) | CD38CYP1A2CYP2C19SCN10AALDH1A1 | |
| SCHEMBL12167268 | 0.67 | CYP1A2 (0.43) | TRPV1CD38CYP1A2CYP2C19LMNA | |
| SCHEMBL19979861 | 0.67 | KMT2A (0.32) | ALDH1A1F9 | |
| SCHEMBL19980191 | 0.65 | CHIA (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |