Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19979964 | 0.78 | SCN10A (0.36) | LMNASCN10ATP53 | |
| SCHEMBL19980138 | 0.78 | TRPV1 (0.39) | LMNASCN10AALDH1A1TP53MAPT | |
| SCHEMBL19980223 | 0.78 | ALDH1A1 (0.36) | SMN1; SMN2LMNASCN10AALDH1A1MAPK1 | |
| SCHEMBL19979960 | 0.77 | TUBB4A (0.38) | LMNATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19979876 | 0.77 | TUBB4A (0.35) | SCN10ATUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL19979928 | 0.72 | POLB (0.43) | LMNASCN10AABCB1ABCG2ALDH1A1 | |
| SCHEMBL22918688 | 0.66 | CTSS (0.35) | SMN1; SMN2ALDH1A1TP53MAPT | |
| SCHEMBL19979956 | 0.66 | ALDH1A1 (0.33) | SMN1; SMN2SCN10AALDH1A1KMT2ATUBB4A | |
| SCHEMBL19979861 | 0.62 | KMT2A (0.32) | ALDH1A1KMT2A | |
| SCHEMBL19979908 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018050677-A1 | HERBICIDAL PYRIDINES | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-22 | — | — | WO | disclosed |