SCHEMBL19979960

SCHEMBL19979960

CN(N)/C(=N\N)NC(=O)c1ccc(C(F)(F)F)nc1Cl

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38
TUBA1C Q9BQE3 1/20 0.38
TUBB6 Q9BUF5 1/20 0.38
TUBB2B Q9BVA1 1/20 0.38
TUBB1 Q9H4B7 1/20 0.38
EGFR P00533 4/20 0.37
SMO Q99835 1/20 0.37
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.34
PDE4A P27815 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19980138 0.78 TRPV1 (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL19979964 0.78 SCN10A (0.36) LMNANPC1RAB9A
SCHEMBL19980223 0.78 ALDH1A1 (0.36) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL19979969 0.77 SMN1; SMN2 (0.37) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL22918688 0.76 CTSS (0.35) RAB9A
SCHEMBL19979876 0.75 TUBB4A (0.35) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL23913889 0.73 SLC6A9 (0.34) EGFRLMNAP2RX7NPC1RAB9A
SCHEMBL13018120 0.71 TUBB4A (0.43) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL22245656 0.70 P2RX7 (0.35) P2RX7
SCHEMBL19616100 0.70 TUBB4A (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018050677-A1 HERBICIDAL PYRIDINES SYNGENTA PARTICIPATIONS AG (CH) 2018-03-22 WO disclosed