Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25135370 | 0.93 | HTR6 (0.41) | DRD2HTR6HTR1B | |
| SCHEMBL19980628 | 0.91 | PTGDR2 (0.34) | DRD2PTGDR2HCRTR1HCRTR2KDM4C | |
| SCHEMBL19972527 | 0.89 | MEN1 (0.32) | DRD2PTGDR2HCRTR1HCRTR2KDM4C | |
| SCHEMBL26036581 | 0.89 | RORC (0.34) | DRD2PTGDR2HCRTR1HCRTR2KDM4C | |
| SCHEMBL19980685 | 0.88 | KDM4C (0.36) | PTGDR2KDM4CMEN1KMT2A | |
| SCHEMBL19972555 | 0.88 | HTR6 (0.38) | DRD2HTR6MEN1KMT2A | |
| SCHEMBL29985977 | 0.88 | HTR6 (0.38) | DRD2HTR6MEN1KMT2A | |
| SCHEMBL31001721 | 0.87 | GPBAR1 (0.40) | — | |
| SCHEMBL23515867 | 0.87 | HCRTR1 (0.32) | PTGDR2HCRTR1HCRTR2 | |
| SCHEMBL19972612 | 0.87 | GPBAR1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4230627-A2 | INHIBITORS OF THE MENIN-MLL INTERACTION | Vitae Pharmaceuticals, LLC (US) | 2023-08-23 | — | — | EP | disclosed |
| EP-3512850-B1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS LLC (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2018053267-A1 | INHIBITORS OF THE MENIN-MLL INTERACTION | VITAE PHARMACEUTICALS, INC. (US) | 2018-03-22 | — | — | WO | disclosed |