Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041635 | 0.89 | TSHR (0.48) | MAOBMAOACYP19A1THRBTSHR | |
| SCHEMBL16693247 | 0.87 | YWHAG (0.40) | MAOBMAOACYP19A1THRBTSHR | |
| SCHEMBL27551658 | 0.85 | LOXL2 (0.44) | THRBNPC1RAB9ATSHRTDP1 | |
| SCHEMBL9817767 | 0.85 | ALDH1A1 (0.42) | MAOBMAOACYP19A1THRBRAB9A | |
| SCHEMBL4690527 | 0.84 | MAOA (0.50) | MAOBMAOACYP19A1THRBNPC1 | |
| SCHEMBL1119153 | 0.84 | TYR (0.56) | THRBTYRCA12CA1CA4 | |
| SCHEMBL31744941 | 0.84 | TYR (0.56) | THRBTYRCA12CA1CA4 | |
| SCHEMBL150133 | 0.84 | ALOX5 (0.49) | MAOBTHRBTDP1POLBAPEX1 | |
| SCHEMBL29734636 | 0.84 | ALOX5 (0.49) | MAOBTHRBTDP1POLBAPEX1 | |
| SCHEMBL28186333 | 0.84 | APP (0.46) | THRBNPC1RAB9ATSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |