Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18256223 | 0.73 | HDAC3 (0.52) | HDAC1HDAC3LMNAHDAC2NCOR2 | |
| SCHEMBL9506673 | 0.72 | PTGER4 (0.40) | PTGER4LMNAALDH1A1MAPT | |
| SCHEMBL19980987 | 0.71 | MTNR1B (0.35) | PTGER4HDAC1HDAC3LMNAALDH1A1 | |
| SCHEMBL28044046 | 0.70 | MTNR1B (0.56) | TP53LMNAALDH1A1CDYLMAPT | |
| SCHEMBL20266373 | 0.70 | PTGER4 (0.64) | PTGER4HDAC1ALDH1A1MAPT | |
| SCHEMBL6334634 | 0.70 | ALDH1A1 (0.45) | PTGER4LMNAALDH1A1MAPTHTT | |
| SCHEMBL17845272 | 0.69 | PTGER4 (0.49) | PTGER4HDAC1HDAC3LMNAALDH1A1 | |
| SCHEMBL31122067 | 0.69 | PTGER4 (0.49) | PTGER4HDAC1HDAC3LMNAALDH1A1 | |
| SCHEMBL11227767 | 0.69 | HDAC1 (0.50) | HDAC1HDAC3ALDH1A1HDAC2NCOR2 | |
| SCHEMBL855211 | 0.69 | PTGER4 (0.51) | PTGER4TP53HDAC1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |