Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19980985 | 0.89 | HDAC1 (0.38) | HDAC3HDAC2HDAC1PTGER4 | |
| SCHEMBL19981012 | 0.86 | HDAC1 (0.33) | HDAC2HDAC1ALDH1A1PTGER4POLB | |
| SCHEMBL19980976 | 0.84 | HDAC1 (0.41) | HDAC3HDAC2HDAC1POLB | |
| SCHEMBL18633372 | 0.82 | THRB (0.37) | MTNR1BMTNR1AMAPK1HDAC3HDAC2 | |
| SCHEMBL22212876 | 0.78 | HDAC1 (0.46) | MTNR1BMTNR1AHDAC3HDAC2HDAC1 | |
| SCHEMBL19980954 | 0.76 | PHLPP2 (0.40) | MAPK1LMNAALDH1A1POLBGAA | |
| SCHEMBL19980979 | 0.75 | S100B (0.48) | LMNAALDH1A1POLB | |
| SCHEMBL19980998 | 0.75 | POLB (0.30) | POLB | |
| SCHEMBL19904093 | 0.72 | S100B (0.55) | MAPK1LMNAALDH1A1POLBGAA | |
| SCHEMBL21117538 | 0.71 | BTK (0.37) | HDAC2HDAC1ALDH1A1PTGER4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |