Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 12/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 5/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | NPC1 | O15118 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10119249 | 0.87 | MYC (0.40) | THRBMYCMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL10039848 | 0.83 | THRB (0.44) | THRBMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL15042117 | 0.77 | MAPT (0.38) | MAPTSMN1; SMN2ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL19396760 | 0.76 | MMP14 (0.42) | MAPTSMN1; SMN2ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL18085861 | 0.76 | THRB (0.36) | THRBMYCMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15003869 | 0.76 | THRB (0.38) | THRBMAPTALDH1A1MAPK1TP53 | |
| SCHEMBL19980951 | 0.75 | MAPT (0.38) | THRBMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL3437427 | 0.75 | THRB (0.39) | THRBMAPTSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL23028973 | 0.74 | MAPT (0.40) | THRBMAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL23028900 | 0.74 | MAPT (0.41) | THRBMAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601268-B1 | PARTICLES FOR ELECTROPHORETIC DISPLAYS | MERCK PATENT GMBH (DE) | 2018-03-21 | — | — | EP | disclosed |