SCHEMBL10119249

SCHEMBL10119249

C=CC(=O)OCCN(CCOC(=O)C=C)c1ccc(/N=N/c2ccc(/N=N/c3ccccc3)cc2)c(C(C)=O)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 1/20 0.40
MAPT P10636 15/20 0.39
L3MBTL1 Q9Y468 10/20 0.39
MAPK1 P28482 9/20 0.39
SMN1; SMN2 Q16637 8/20 0.39
LMNA P02545 5/20 0.39
TP53 P04637 3/20 0.39
ALDH1A1 P00352 2/20 0.39
THRB P10828 1/20 0.38
HTT P42858 7/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
POLB P06746 2/20 0.35
TDP1 Q9NUW8 5/20 0.34
GAA P10253 2/20 0.34
RAB9A P51151 5/20 0.34
NPC1 O15118 4/20 0.34
HPGD P15428 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
PTBP1 P26599 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10119169 0.87 MYC (0.40) MYCMAPTL3MBTL1MAPK1SMN1; SMN2
SCHEMBL19981023 0.87 THRB (0.38) MYCMAPTL3MBTL1MAPK1SMN1; SMN2
SCHEMBL10039848 0.80 THRB (0.44) MAPTL3MBTL1MAPK1SMN1; SMN2LMNA
SCHEMBL19980935 0.77 THRB (0.36) MAPTTP53ALDH1A1THRBMEN1
SCHEMBL19396760 0.75 MMP14 (0.42) MAPTL3MBTL1MAPK1SMN1; SMN2LMNA
SCHEMBL15003869 0.75 THRB (0.38) MAPTMAPK1TP53ALDH1A1THRB
SCHEMBL19980951 0.74 MAPT (0.38) MAPTL3MBTL1MAPK1SMN1; SMN2LMNA
SCHEMBL15042117 0.74 MAPT (0.38) MAPTL3MBTL1MAPK1SMN1; SMN2LMNA
SCHEMBL9172224 0.74 HTT (0.45) MYCMAPTL3MBTL1MAPK1SMN1; SMN2
SCHEMBL9172233 0.74 HTT (0.45) MYCMAPTL3MBTL1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2601268-B1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2018-03-21 EP disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 US disclosed
US-9487611-B2 Particles for electrophoretic displays MERCK PATENT GMBH (DE) 2016-11-08 US disclosed
US-20130208344-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
US-20130208344-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2013-08-15 US disclosed
WO-2012019704-A1 PARTICLES FOR ELECTROPHORETIC DISPLAYS MERCK PATENT GMBH (DE) 2012-02-16 WO disclosed