Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSA | P10619 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | BLVRB | P30043 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | BMP1 | P13497 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.36 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24218494 | 0.92 | LMNA (0.45) | LMNATSHRCTSAMAOABLVRB | |
| SCHEMBL19981248 | 0.91 | CTSA (0.47) | LMNATSHRCTSAMAOABLVRB | |
| SCHEMBL19981240 | 0.87 | LMNA (0.40) | LMNATSHRCTSAMAOABLVRB | |
| SCHEMBL19981269 | 0.81 | CTSA (0.45) | LMNATSHRCTSAROCK2ROCK1 | |
| SCHEMBL18077932 | 0.78 | VSIR (0.43) | LMNATSHRCTSAHDAC6S1PR1 | |
| SCHEMBL19867036 | 0.78 | VSIR (0.43) | LMNATSHRCTSAHDAC6S1PR1 | |
| SCHEMBL19981137 | 0.77 | S1PR1 (0.38) | LMNATSHRCTSAHDAC6S1PR1 | |
| SCHEMBL19867021 | 0.69 | VSIR (0.48) | CTSAS1PR1 | |
| SCHEMBL18077943 | 0.69 | VSIR (0.48) | CTSAS1PR1 | |
| SCHEMBL19981130 | 0.68 | CTSA (0.41) | LMNATSHRCTSAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018051254-A1 | CYCLIC SUBSTITUTED-1,2,4-OXADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) | 2018-03-22 | — | — | WO | disclosed |